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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-AZD3632
AZD3632

Chemical Structure : AZD3632

CAS No.: 3058433-50-1

AZD3632 (AZD-3632)

货号: PC-28070Not For Human Use, Lab Use Only.

AZD3632 (AZD-3632) is a potent, selective and orally active second-generation menin inhibitor, disrupts the Menin-KMT2A complex, suppresses leukemogenic transcription and promotes malignant cell differentiation. 

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AZD3632 (AZD-3632) is a potent, selective and orally active second-generation menin inhibitor, disrupts the Menin-KMT2A complex, suppresses leukemogenic transcription and promotes malignant cell differentiation. 

物理化学性质&存储条件

分子量 589.76
分子式 C34H44FN5O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, 2-[3-[[1-[[(2S)-5,5-dimethyl-2-pyrrolidinyl]carbonyl]-4-piperidinyl]carbonyl]-2-methyl-1H-pyrrolo[2,3-c]pyridin-1-yl]-5-fluoro-N,N-bis(1-methylethyl)-, (2S)-

参考文献

1. Patent WO2024201240 A1 2024-10-03.

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