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首页-小分子抑制剂&激动剂-Tyrosine Kinase-PDGFR-AZD2932
AZD2932

Chemical Structure : AZD2932

CAS No.: 883986-34-3

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AZD2932 (AZD-2932)

货号: PC-45430Not For Human Use, Lab Use Only.

AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.

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10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AZD2932 is a potent multikinase inhibitor that inhibits PDGFRβ, VEGFR-2, Flt-3 and CSF-1R with IC50 of 4, 8, 100, and 7 nM, respectively.
AZD2932 shows tumor growth inhibition in in vivo model; orally bioavailable.

物理化学性质&存储条件

分子量 447.4864
分子式 C24H25N5O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 41 mg/mL
Chemical Name/SMILES

Benzeneacetamide, 4-[(6,7-dimethoxy-4-quinazolinyl)oxy]-N-[1-(1-methylethyl)-1H-pyrazol-4-yl]-

参考文献

1. Plé PA, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):262-6.

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