AZD1152-HQPA |CAS:722544-51-6 Probechem Biochemicals

Chemical Structure : AZD1152-HQPA

CAS No.: 722544-51-6

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AZD1152-HQPA (Barasertib;AZD2811)

货号: PC-42340Not For Human Use, Lab Use Only.

The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM.

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50 mg	￥4288.0	In stock
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生物&药学活性

The active product of AZD1152, a potent, selective inhibitor of Aurora B kinase with IC50 of 0.37 nM; displays >3,700-fol selectivity for Aurora B over Aurora A; potently inhibits the growth of human colon, lung, and hematologic tumor xenografts.

物理化学性质&存储条件

分子量	507.5599
分子式	C26H30FN7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-

参考文献

1. Grundy M, et al. Mol Cancer Ther. 2010 Mar;9(3):661-72.

2. Mortlock AA, et al. J Med Chem. 2007 May 3;50(9):2213-24. Epub 2007 Mar 21.

3. Wilkinson RW, et al. Clin Cancer Res. 2007 Jun 15;13(12):3682-8.

AZD1152-HQPA (Barasertib;AZD2811)

生物&药学活性

物理化学性质&存储条件

参考文献

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AZD1152-HQPA (Barasertib;AZD2811)

生物&药学活性

物理化学性质&存储条件

参考文献

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