Chemical Structure : AZD1092
货号: PC-61877Not For Human Use, Lab Use Only.
AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM.
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AZD1092 (GKA-80) is a potent Glucokinase (GK) activator with EC50 of 30 nM.
AZD1092 exhibits dose dependent reduction of glucose excursion in oral glucose tolerance tests in high fat fed female Zucker rats.
AZD1092 shows potential for treatment of type 2 diabetes.
分子量 | 450.495 | |
分子式 | C24H26N4O5 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Coope GJ, et al. Br J Pharmacol. 2006 Oct;149(3):328-35.
2. Michael J. Waring, et al. Med. Chem. Commun., 2011, 2, 775-779
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