Atecegatran metoxil (AZD0837) | Thrombin inhibitor | Probechem Biochemicals

Chemical Structure : AZD0837

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AZD0837 (Atecegatran metoxil, AZD-0837)

货号: PC-63163Not For Human Use, Lab Use Only.

Atecegatran metoxil (AZD0837) is an oral anticoagulant that after bioconversion to its active form AR-H067637, which is a potent and reversible thrombin inhibitor.

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生物&药学活性

Atecegatran metoxil (AZD0837) is an oral anticoagulant that after bioconversion to its active form AR-H067637, which is a potent and reversible thrombin inhibitor.

物理化学性质&存储条件

分子量	496.896
分子式	C22H23ClF2N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)-N-(4-(N-methoxycarbamimidoyl)benzyl)azetidine-2-carboxamide

参考文献

1. Schützer KM, et al. Eur J Clin Pharmacol. 2010 Sep;66(9):903-10.

2. Lip GY, et al. Thromb Res. 2011 Feb;127(2):91-9.

3. Matsson EM, et al. Mol Pharm. 2013 Nov 4;10(11):4252-62.

4. Deinum J, et al. Thromb Haemost. 2009 Jun;101(6):1051-9.

AZD0837 (Atecegatran metoxil, AZD-0837)

生物&药学活性

物理化学性质&存储条件

参考文献

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AZD0837 (Atecegatran metoxil, AZD-0837)

生物&药学活性

物理化学性质&存储条件

参考文献

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