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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-AX20017
AX20017

Chemical Structure : AX20017

CAS No.: 329221-38-7

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AX20017 (AX 20017)

货号: PC-73194Not For Human Use, Lab Use Only.

AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM.

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10 mg ￥680 In stock
25 mg ￥1180 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AX20017 is a highly selective inhibitor of Mycobacterium tuberculosis protein kinase G (PknG) with IC50 of 0.39 uM.
AX20017 is buried deep within the adenosine-binding site, targeting an active conformation of the kinase domain.
AX20017 is a reference to determine candidate compounds that can act as potential inhibitors for PknG as anti-mycobacterium tuberculosis compounds.

物理化学性质&存储条件

分子量 268.37
分子式 C13H20N2O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(Cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide

参考文献

1. Walburger A, et al. Science. 2004 Jun 18;304(5678):1800-4.

2. Scherr N, et al. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12151-6.

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