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首页-小分子抑制剂&激动剂-Immunology/Inflammation-T Cell Receptor (TCR)-AX-000
AX-000

Chemical Structure : AX-000

CAS No.: 340014-88-2

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AX-000 (AX000, AX 000)

货号: PC-60399Not For Human Use, Lab Use Only.

AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AX-000 is a hit compound that inhibits the proliferation of human peripheral blood T cells stimulated with anti-CD3 with IC50 of <10 nM, inhibits TCR-Nck interaction.

    物理化学性质&存储条件

    分子量 381.519
    分子式 C27H27NO
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-((2,4-diphenyl-4H-chromen-3-yl)methyl)piperidine

    参考文献

    1. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184.

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