AVG-388 | RSV RdRP inhibitor | Probechem Biochemicals

Chemical Structure : AVG-388

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AVG-388 (AVG388)

货号: PC-47082Not For Human Use, Lab Use Only.

AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo.

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生物&药学活性

AVG-388 is a potent, allosteric, orally efficacious inhibitor of respiratory syncytial virus (RSV) RNA synthesis, potently blocks RSV RNA-dependent RNA polymerase (RdRP) bioactivity, exhibits strong antiviral efficacy in vivo.

物理化学性质&存储条件

分子量	629.443
分子式	C27H16F9N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3,5-difluoropyridin-2-yl)-4-methyl-1-(2,3,5,6-tetrafluoro-4-methoxybenzyl)-5-((6-(trifluoromethyl)pyridin-2-yl)methyl)-1,2-dihydro-3H-pyrazolo[4,3-c]pyridine-3,6(5H)-dione

参考文献

1. Julien Sourimant, et al. Sci Adv. 2022 Jun 24;8(25):eabo2236.

AVG-388 (AVG388)

生物&药学活性

物理化学性质&存储条件

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AVG-388 (AVG388)

生物&药学活性

物理化学性质&存储条件

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