AUDA-BE | sEH inhibitor | Probechem Biochemicals

Chemical Structure : AUDA-BE

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AUDA-BE (sEH inhibitor)

货号: PC-70251Not For Human Use, Lab Use Only.

AUDA-BE is the prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

AUDA-BE is the prodrug of AUDA, a potent inhibitor of sEH (soluble epoxide hydrolase) with IC50 of 50 nM and 100 nM for mouse sEH and human sEH, respectively.
AUDA-BE prevents LPS-induced mortality and preserved systolic blood pressure, reduces NO production in mice.

物理化学性质&存储条件

分子量	448.692
分子式	C27H48N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	butyl 12-(3-(adamantan-1-yl)ureido)dodecanoate

参考文献

1. Morisseau C, et al. Biochem Pharmacol. 2002 May 1;63(9):1599-608.

2. Schmelzer KR, et al. Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9772-7.

3. Motoki A, et al. Am J Physiol Heart Circ Physiol. 2008 Nov;295(5):H2128-34.