ATM-3507 |CAS:1861449-70-8 Probechem Biochemicals

Chemical Structure : ATM-3507

CAS No.: 1861449-70-8

加入收藏

ATM-3507 (ATM3507;ATM 3507)

货号: PC-35924Not For Human Use, Lab Use Only.

ATM-3507 (ATM3507) is a small molecule inhibitor of Tpm3.1 tropomyosin isoform, disrupts Tpm3.1-containing microfilaments in SK-N-SH cells at 5 uM.

规格	价格	库存
5 mg	￥2280	In stock
10 mg	￥3680	In stock
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ATM-3507 (ATM3507) is a small molecule inhibitor of Tpm3.1 tropomyosin isoform, disrupts Tpm3.1-containing microfilaments in SK-N-SH cells at 5 uM.
ATM-3507 shows cancer cell cytotoxicity comparable with the first-in-class tool compound TR100.
ATM-3507 also shows a strong synergistic effect when TR100 or ATM-3507 were combined with antimicrotubule agents in both in vitro and in vivo neuroblastoma models.

物理化学性质&存储条件

分子量	611.806
分子式	C37H46FN5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3-((2,3-dimethyl-1-(3-(4-methylpiperazin-1-yl)propyl)-1H-indol-5-yl)oxy)phenyl)(4-(4-fluorophenethyl)piperazin-1-yl)methanone

参考文献

1. Currier MA, et al. Mol Cancer Ther. 2017 Aug;16(8):1555-1565.

2. Mitchell CB, et al. Cytoskeleton (Hoboken). 2018 Jul;75(7):307-317.

ATM-3507 (ATM3507;ATM 3507)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ATM-3507 (ATM3507;ATM 3507)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.