ATI-2341 | CXCR4 agonist | Probechem Biochemicals

Chemical Structure : ATI-2341

CAS No.: 1337878-62-2

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ATI-2341 (ATI 2341, ATI2341)

货号: PC-60592Not For Human Use, Lab Use Only.

ATI-2341 is a potent, selective and allosteric CXCR4 agonist with EC50 of 194 nM.

规格	价格	库存
5 mg	￥1980	In stock
10 mg	￥3280	In stock
25 mg	￥5280	In stock
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100 mg		Get quote

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生物&药学活性

ATI-2341 is a potent, selective and allosteric CXCR4 agonist with EC50 of 194 nM.
ATI-2341 induces CXCR4-dependent calcium flux in U87 glioblastoma cells (IC50=140 nM), receptor internalization, and chemotaxis in cell-based assays.
ATI-2341 also displays potent efficacy in the mobilization of PMNs and HSPCs in mice and nonhuman primates.

物理化学性质&存储条件

分子量	2256.82
分子式	C104H178N26O25S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Leucine, N-(1-oxohexadecyl)-L-methionylglycyl-L-tyrosyl-L-glutaminyl-L-lysyl-L-lysyl-L-leucyl-L-arginyl-L-seryl-L-methionyl-L-threonyl-L-α-aspartyl-L-lysyl-L-tyrosyl-L-arginyl-

参考文献

1. Tchernychev B, et al. Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22255-9.

2. Janz JM, et al. J Am Chem Soc. 2011 Oct 12;133(40):15878-81.

3. Quoyer J, et al. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):E5088-97.

4. Luo J, et al. Mol Pharmacol. 2017 Jun;91(6):554-566.

ATI-2341 (ATI 2341, ATI2341)

生物&药学活性

物理化学性质&存储条件

参考文献

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ATI-2341 (ATI 2341, ATI2341)

生物&药学活性

物理化学性质&存储条件

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