ASP7967 | RNA aptamer AC17-4 ligand | Probechem Biochemicals

Chemical Structure : ASP7967

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ASP7967 (ASP-7967, ASP 7967)

货号: PC-20404Not For Human Use, Lab Use Only.

规格	价格	库存	数量
50 mg		Get quote
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250 mg		Get quote

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生物&药学活性

ASP7967 (ASP-7967) is a cell-permeable and low-toxic compound of RNA aptamer AC17-4 with SPR binding Kd of 12 nM, activates gene expression (>10-fold) in aptazyme-based riboswitches with EC50 of 2.3 uM.
Oral administration of 100 mg/kg ASP7967 upregulated the serum hEPO concentration by ∼7.2-fold over the vehicle control in mice.

物理化学性质&存储条件

分子量	406.40
分子式	C20H16F2N8
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N2,N4-bis(4-fluorophenyl)-N6-(pyrimidin-2-ylmethyl)-1,3,5-triazine-2,4,6-triamine

参考文献

1. Keisuke Fukunaga, et al. J Am Chem Soc. 2023 Mar 29. doi: 10.1021/jacs.2c12332.

ASP7967 (ASP-7967, ASP 7967)

生物&药学活性

物理化学性质&存储条件

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ASP7967 (ASP-7967, ASP 7967)

生物&药学活性

物理化学性质&存储条件

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