AS2575959 |CAS:1616871-34-1 Probechem Biochemicals

Chemical Structure : AS2575959

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AS2575959 (AS 2575959;AS-2575959)

货号: PC-60999Not For Human Use, Lab Use Only.

AS2575959 is a novel potent, specific, orally available GPR40 agonist that influences glucose-dependent insulin secretion both in vitro pancreas β-cell-derived cells and in vivo.

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生物&药学活性

AS2575959 is a novel potent, specific, orally available GPR40 agonist that influences glucose-dependent insulin secretion both in vitro pancreas β-cell-derived cells and in vivo.
AS2575959 demonstrates a synergistic effect on insulin secretion and plasma GLP-1 level combined with DPP-IV inhibitor.

物理化学性质&存储条件

分子量	554.615
分子式	C32H35NaO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Sodium [(3S)-6-({4'-[(3S)-3,4-dihydroxybutoxy]-2,2',6'-trimethyl[1,1'-biphenyl]-3-yl}methoxy)-3H-spiro[1-benzofuran-2,1'-cyclopropan]-3-yl]acetate

参考文献

1. Tanaka H, et al. Life Sci. 2014 Jan 17;94(2):115-21.

AS2575959 (AS 2575959;AS-2575959)

生物&药学活性

物理化学性质&存储条件

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AS2575959 (AS 2575959;AS-2575959)

生物&药学活性

物理化学性质&存储条件

参考文献

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