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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-AMPK-ARUK2010489
ARUK2010489

Chemical Structure : ARUK2010489

CAS No.:

ARUK2010489 (ARUK-2010489)

货号: PC-25727Not For Human Use, Lab Use Only.

ARUK2010489 is a potent, selective and highly brain penetrant NUAK1 inhibitor with pIC50 of 8.7, displays no CDK2 activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ARUK2010489 is a potent, selective and highly brain penetrant NUAK1 inhibitor with pIC50 of 8.7, displays no CDK2 activity.

物理化学性质&存储条件

分子量 406.53
分子式 C23H30N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(cyclopropylmethoxy)-N-(4-(4-isopropylpiperazin-1-yl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine

参考文献

1. Aldred GG, et al. ACS Med Chem Lett. 2025 Sep 10;16(11):2264-2272.

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