ARP101 | MMP-2 inhibitor | Probechem Biochemicals

Chemical Structure : ARP101

CAS No.: 849773-63-3

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ARP101 (ARP-101, ARP 101)

货号: PC-35730Not For Human Use, Lab Use Only.

ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.

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10 mg	￥3880	In stock
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生物&药学活性

ARP101 (ARP-101) is a selective MMP-2 inhibitor, induces autophagy-associated cell death in cancer cells.
ARP101 (ARP-101) was highly effective in inducing the formation of autophagosome and conversion of LC3I into LC3II.
ARP101-induced autophagy was completely blocked in mouse embryo fibroblasts that lacked autophagy related gene 5 (ATG5(-/-) MEF).
ARP101 inhibits α-MSH-stimulated melanogenesis by regulation of autophagy in melanocytes.

物理化学性质&存储条件

分子量	406.497
分子式	C20H26N2O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-hydroxy-2-(N-isopropoxy-[1,1'-biphenyl]-4-sulfonamido)-3-methylbutanamide

参考文献

1. Jo YK, et al. Biochem Biophys Res Commun. 2011 Jan 28;404(4):1039-43.

2. Kim ES, et al. FEBS Lett. 2013 Dec 11;587(24):3955-60.

ARP101 (ARP-101, ARP 101)

生物&药学活性

物理化学性质&存储条件

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ARP101 (ARP-101, ARP 101)

生物&药学活性

物理化学性质&存储条件

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