Chemical Structure : ARN25068
CAS No.: 2649882-80-2
货号: PC-38653Not For Human Use, Lab Use Only.
ARN25068 is a highly potent, triple GSK-3β/FYN/DYRK1A inhibitor with IC50 of 4.17 and 2.17 μM for GSK-3β and FYN, reduces the extent of tau phosphorylation in Tau0N4R-TM-tGFP U2OS cell line.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1980 | In stock | |
10 mg | ¥2980 | In stock | |
25 mg | ¥4980 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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ARN25068 is a highly potent, triple GSK-3β/FYN/DYRK1A inhibitor with IC50 of 4.17 and 2.17 μM for GSK-3β and FYN, reduces the extent of tau phosphorylation in Tau0N4R-TM-tGFP U2OS cell line.
分子量 | 362.455 | |
分子式 | C19H18N6S | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N2-benzyl-N4-(3-cyclopropyl-1H-pyrazol-5-yl)thieno[3,2-d]pyrimidine-2,4-diamine |
1. Stefania Demuro, et al. Eur J Med Chem. 2022 Feb 5;229:114054.
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