ARM-1 |CAS:68729-05-5 Probechem Biochemicals

Chemical Structure : ARM-1

CAS No.: 68729-05-5

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ARM-1 (ARM1, 4BSA)

货号: PC-70333Not For Human Use, Lab Use Only.

ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.

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10 mg	￥1380	In stock
25 mg	￥2180	In stock
50 mg	￥3780	In stock
100 mg		Get quote

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生物&药学活性

ARM-1 is a novel LTA4 hydrolase (LTA4H) inhibitor that inhibits LTB4 synthesis in human neutrophils with IC50 of 0.5 uM.
ARM-1 selectively blocks conversion of LTA4 into LTB4, sparing the enzyme's anti-inflammatory aminopeptidase activity.
ARM-1 represents a new class of LTA4 hydrolase inhibitor that holds promise for improved anti-inflammatory properties.

物理化学性质&存储条件

分子量	268.4
分子式	C16H16N2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-benzylphenyl)thiazol-2-amine

参考文献

1. Stsiapanava A, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4227-32.

ARM-1 (ARM1, 4BSA)

生物&药学活性

物理化学性质&存储条件

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ARM-1 (ARM1, 4BSA)

生物&药学活性

物理化学性质&存储条件

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