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首页-小分子抑制剂&激动剂-GPCR-Mas-related G protein-coupled receptor (MRGPR)-AR234958
AR234958

Chemical Structure : AR234958

CAS No.:

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AR234958 (AR-234958)

货号: PC-26492Not For Human Use, Lab Use Only.

AR234958 is a selective pharmacological activator of orphan GPCR Mas1 with pEC50 of 6.71, demonstrates superior efficacy compared to the peptide ligands NPFF, Ang-(1-7).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AR234958 is a selective pharmacological activator of orphan GPCR Mas1 with pEC50 of 6.71, demonstrates superior efficacy compared to the peptide ligands NPFF, Ang-(1-7).

物理化学性质&存储条件

分子量 572.63
分子式 C28H30F2N4O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(4-fluorophenyl)-4-((4-(3-fluorophenyl)-1-((2-methoxy-4-nitrophenyl)sulfonyl)pyrrolidin-3-yl)methyl)piperazine

参考文献

1. Zhang Y, et al. EMBO J. 2026 Mar 30. doi: 10.1038/s44318-026-00764-6.

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