AR-C118925 | P2Y2R antagonist | Probechem Biochemicals

Chemical Structure : AR-C118925

加入收藏

AR-C118925 (AR-C 118925)

货号: PC-20993Not For Human Use, Lab Use Only.

AR-C118925 is a potent, selective, competitive P2Y2 receptor antagonist with pA2 values of 37.2 nM and 51.3 nM in calcium and β-arrestin assays, respectively.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

AR-C118925 is a potent, selective, competitive P2Y2 receptor antagonist with pA2 values of 37.2 nM and 51.3 nM in calcium and β-arrestin assays, respectively.
AR-C118925 inhibits UTP-induced receptor activation with an IC50 value of 37.1 nM at the human P2Y4 receptor, at least 500-fold selective for the P2Y2 over the P2Y4 receptor.
AR-C118925 is at least 50-fold selective for the P2Y2 receptor over any other mammalian P2Y receptor subtype.
AR-C118925 is a useful pharmacological tool for in vitro as well as in vivo studies of P2Y2 receptors.

物理化学性质&存储条件

分子量	537.60
分子式	C28H23N7O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(C1=CC=C(CN(C(N2)=O)C=C(C3C4=CC=C(C)C=C4C=CC5=CC(C)=CC=C35)C2=S)O1)NC6=NN=NN6

参考文献

1. Hochhauser E, et al. Purinergic Signal. 2013 Dec;9(4):633-42.

2. Rafehi M, et al. Purinergic Signal. 2017 Mar;13(1):89-103.

3. Patent WO1998054180

AR-C118925 (AR-C 118925)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

AR-C118925 (AR-C 118925)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.