欢迎访问ProbeChem中文网站,英文网站请访问www.probechem.com

首页-小分子抑制剂&激动剂-Immunology/Inflammation-Nitric Oxide Synthase (NOS)-AR-C102222
AR-C102222

Chemical Structure : AR-C102222

CAS No.: 253771-21-0

AR-C102222 (AR-C 102222)

货号: PC-62230Not For Human Use, Lab Use Only.

AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively.

规格 价格 库存 数量
25 mg Get quote
100 mg Get quote
200 mg Get quote
1 g Get quote

大包装,大折扣!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AR-C102222 is a potent, selective iNOS inhibitor with IC50 of 35 nM, dislapys 3,000-fold and 20-fold selectivity over eNOS and nNOS respectively.
    AR-C102222 reduces inflammation produced by the application of arachidonic acid to the ear, attenuates FCA-induced mechanical hyperalgesia, and attenuates acetic acid-induced writhing in mice.

    物理化学性质&存储条件

    分子量 382.375
    分子式 C19H16F2N6O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    Spiro[piperidine-4,2'(1'H)-quinazolin]-4'-amine, 1-[(6-cyano-3-pyridinyl)carbonyl]-5',8'-difluoro- (9CI)

    参考文献

    1. Garcin ED, et al. Nat Chem Biol. 2008 Nov;4(11):700-7.

    2. Tinker AC, et al. J Med Chem. 2003 Mar 13;46(6):913-6.

    3. LaBuda CJ, et al. Eur J Pain. 2006 Aug;10(6):505-12.

    备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: