ANY1 |CAS:482574-02-7 Probechem Biochemicals

Chemical Structure : ANY1

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ANY1 (FosA inhibitor ANY1)

货号: PC-36006Not For Human Use, Lab Use Only.

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).

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生物&药学活性

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).
ANY1 binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM.
ANY1 potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens.

物理化学性质&存储条件

分子量	537.088
分子式	C15H7Br2N9O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-bromo-6-[3-(3-bromo-2-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl)-4-nitro-1H-pyrazol-5-yl]-1H-pyrazolo[1,5-a]pyrimidin-2-one

参考文献

1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18.

ANY1 (FosA inhibitor ANY1)

生物&药学活性

物理化学性质&存储条件

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ANY1 (FosA inhibitor ANY1)

生物&药学活性

物理化学性质&存储条件

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