ANT3310 sodium (Pilabactam)

Chemical Structure : ANT3310 sodium

CAS No.: 2410688-61-6

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货号: PC-24831Not For Human Use, Lab Use Only.

ANT3310 sodium (Pilabactam) is a potent, covalent broad-spectrum serine β-Lactamase inhibitor with IC50 of 1-175 nM against a panel of serine β-Lactamases.

规格	价格	库存
5 mg	￥780	In stock
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ANT3310 sodium (Pilabactam) is a potent, covalent broad-spectrum serine β-Lactamase inhibitor with IC50 of 1-175 nM against a panel of serine β-Lactamases.
ANT3310 is a very good inhibitor of OXA-23, as well as OXA-48, but not avibactam.
ANT3310 is equipotent against KPC- and OXA-CRE while superior against OXA-CRAB.
ANT3310 is effective against CREs and A. baumannii strains and is efficacious in mouse infection models.

物理化学性质&存储条件

分子量	262.19
分子式	C6H8FN2NaO5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium (2R,5R)-2-fluoro-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate

参考文献

1. Davies DT, et al. J Med Chem. 2020 Dec 24;63(24):15802-15820.