AN-12-H5 |CAS:1193340-31-6 Probechem Biochemicals

Chemical Structure : AN-12-H5

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AN-12-H5 (Enterovirus inhibitor)

货号: PC-62927Not For Human Use, Lab Use Only.

AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.

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生物&药学活性

AN-12-H5 is a bifunctional, enviroxime-like anti-Enterovirus compound that inhibits replication and the early stage of enterovirus 71 infection with EC50 of 0.55 uM.
Mutations in capsid proteins (G3112A, VP1-Ala224Thr, and G2396A, VP3-Arg227Lys mutations) are resistant to AN-12-H5.

物理化学性质&存储条件

分子量	513.645
分子式	C24H23N3O4S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((6aS,8S)-2-(4-(methylthio)phenyl)-6,12-dioxo-5,6,6a,7,8,9,10,12-octahydrobenzo[e]pyrido[1,2-a][1,4]diazepin-8-yl)thiophene-2-sulfonamide

参考文献

1. Arita M, et al. J Gen Virol. 2010 Nov;91(Pt 11):2734-44.

2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.

3. Arita M, et al. J Virol. 2013 Apr;87(8):4252-60.

AN-12-H5 (Enterovirus inhibitor)

生物&药学活性

物理化学性质&存储条件

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AN-12-H5 (Enterovirus inhibitor)

生物&药学活性

物理化学性质&存储条件

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