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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Complement System-AMY-101
AMY-101

Chemical Structure : AMY-101

CAS No.: 1427001-89-5

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AMY-101 (Cp40, AMY101)

货号: PC-72455Not For Human Use, Lab Use Only.

AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.

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5 mg ￥2480 In stock
10 mg ￥3980 In stock
25 mg ￥5980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AMY-101 (Cp40) is a peptidic inhibitor of the central complement component C3 for the management of patients with ARDS caused by SARS-CoV-2 infection.
AMY-101 is a novel complement C3-targeted therapeutic based on the 3 rd-generation compstatin analog Cp40.

物理化学性质&存储条件

分子量 1789.11
分子式 C83H117N23O18S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

YICV-{Trp(Me)}-QDW-{Sar}-AHRC-{N(Me)Ile}-NH2 (Disulfide bridge:Cys3-Cys13)

参考文献

1. Bostanci N, et al. J Proteome Res. 2018 Sep 7;17(9):3153-3175.

2. Reis ES, et al. Clin Immunol. 2018 Dec;197:96-106.

3. Mastellos DC, et al. Clin Immunol. 2020 Nov;220:108598.

4. Hasturk H, et al. J Clin Invest. 2021 Dec 1;131(23):e152973.

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