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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-AMPK-AMPK activator 991
AMPK activator 991

Chemical Structure : AMPK activator 991

CAS No.: 1219739-95-3

AMPK activator 991

货号: PC-35496Not For Human Use, Lab Use Only.

AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro, binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AMPK activator 991 is an allosteric AMPK activator, activates non-phosphorylated Thr172 AMPK in vitro, binds to α1β1γ1 and α2β1γ1 with Kd of 0.13 and 0.17 uM, respectively.

    物理化学性质&存储条件

    分子量 431.876
    分子式 C24H18ClN3O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-((5-chloro-6-(1-methyl-1H-indol-6-yl)-1H-benzo[d]imidazol-2-yl)oxy)-2-methylbenzoic acid

    参考文献

    1. Willows R, et al. Biochem J. 2017 Aug 22;474(17):3059-3073.

    2. Ngoei KRW, et al. Cell Chem Biol. 2018 Jun 21;25(6):728-737.e9.

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