AMPK activator 13 |CAS:1243184-62-4 Probechem Biochemicals

Chemical Structure : AMPK activator 13

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AMPK activator 13 (AMPK-Activator-13)

货号: PC-60202Not For Human Use, Lab Use Only.

AMPK activator 13 is a potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).

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生物&药学活性

AMPK activator 13 is a potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).
AMPK activator 13 inhibits de novo lipogenesis in cellular and animal models of hyperlipidemia.
AMPK activator 13 the cell-permeable prodrug of compound 2 (AMPK-Activator-2).

物理化学性质&存储条件

分子量	431.334
分子式	C17H22NO10P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(((5-(5-oxo-4,5-dihydroisoxazol-3-yl)furan-2-yl)phosphoryl)bis(oxy))bis(methylene) bis(2-methylpropanoate)

参考文献

1. Hunter RW, et al. Chem Biol. 2014 Jul 17;21(7):866-79.

2. Gómez-Galeno JE, et al. ACS Med Chem Lett. 2010 Aug 30;1(9):478-82.

AMPK activator 13 (AMPK-Activator-13)

生物&药学活性

物理化学性质&存储条件

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AMPK activator 13 (AMPK-Activator-13)

生物&药学活性

物理化学性质&存储条件

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