Chemical Structure : AMG650
CAS No.: 2410796-79-9
货号: PC-72904Not For Human Use, Lab Use Only.
AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1580 | In stock | |
10 mg | ¥2480 | In stock | |
25 mg | ¥3980 | In stock | |
50 mg | ¥5980 | In stock | |
100 mg | Get quote |
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AMG650 (Sovilnesib) is an oral, first in class, selective small molecule inhibitor of KIF18A with IC50 of 71 nM.
KIF18A is a mitotic kinesin motor protein that regulates chromosome positioning during cell division and is overexpressed in a subset of human cancers.
分子量 | 564.653 | |
分子式 | C26H34F2N6O4S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide |
1, Patent WO2021211549.
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