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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-γ-secretase-AMG2008827
AMG2008827

Chemical Structure : AMG2008827

CAS No.:

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AMG2008827 (AMG-2008827;AMG 2008827)

货号: PC-60978Not For Human Use, Lab Use Only.

A potent, selective γ-secretase inhibitor that significantly reduces the right ventricular systolic pressure and right heart hypertrophy in hypoxia/SU5416 (SUHx) rats..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AMG2008827 is a potent, selective γ-secretase inhibitor that significantly reduces the right ventricular systolic pressure and right heart hypertrophy in hypoxia/SU5416 (SUHx) rats.

    物理化学性质&存储条件

    分子量
    分子式
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    参考文献

    1. Dabral S, et al. Eur Respir J. 2016 Oct;48(4):1137-1149.

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