Chemical Structure : AMG151
货号: PC-49834Not For Human Use, Lab Use Only.
AMG 151 (ARRY-403) is an orally available allosteric glucokinase (GK) activator, binds to glucose-bound glucokinase distinctly from glucose- or adenosine triphosphate-binding sites to activate glucokinase selectively.
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AMG 151 (ARRY-403) is an orally available allosteric glucokinase (GK) activator, binds to glucose-bound glucokinase distinctly from glucose- or adenosine triphosphate-binding sites to activate glucokinase selectively.
分子量 | 454.52 | |
分子式 | C20H18N6O3S2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. John Chung, et al. J Pharm Sci. 2015 Apr;104(4):1522-32.
2. Katz L, et al. Diabetes Obes Metab. 2016 Feb;18(2):191-5.
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