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AM4085

Chemical Structure : AM4085

CAS No.:

AM4085 (AM 4085)

货号: PC-21823Not For Human Use, Lab Use Only.

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AM4085 is a potent, orally bioavailable lectin domain of FmLH antagonist with IC50 of 0.19 uM.
AM4085 a promising lead candidate worthy of further potency optimization and biological evaluation in advanced preclinical studies in the treatment of chronic urinary tract infections (UTIs) of the bladder and kidney.

物理化学性质&存储条件

分子量 459.39
分子式 C21H21F4NO6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((2S,3R,4R,5R,6R)-2-((4'-fluoro-6-(trifluoromethyl)-[1,1'-biphenyl]-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide

参考文献

1. Maddirala AR, et al. J Med Chem. 2024 Feb 3. doi: 10.1021/acs.jmedchem.3c02128.

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