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首页-小分子抑制剂&激动剂-GPCR-Cannabinoid Receptor-AM10257
AM10257

Chemical Structure : AM10257

CAS No.: 2316841-32-2

AM10257 (AM-10257)

货号: PC-22167Not For Human Use, Lab Use Only.

AM10257 is a potent, selective cannabinoid receptor 2 (CB2) antagonist with IC50 of 47 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AM10257 is a potent, selective cannabinoid receptor 2 (CB2) antagonist with IC50 of 47 nM.

物理化学性质&存储条件

分子量 421.59
分子式 C26H35N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(adamantan-1-yl)-1-(5-hydroxypentyl)-4-methyl-5-phenyl-1H-pyrazole-3-carboxamide

参考文献

1. Hu T, et al. J Med Chem. 2021 Sep 23;64(18):13752-13765.

2. Li X, et al. Cell. 2019 Jan 24;176(3):459-467.e13.

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