AM-8123 | Apelin receptor agonist | Probechem Biochemicals

Chemical Structure : AM-8123

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AM-8123 (AM8123)

货号: PC-38137Not For Human Use, Lab Use Only.

AM-8123 (AM8123) is a small-molecule agonist of Apelin receptor (APJ, APLNR), inhibits forskolin-stimulated cAMP production (pEC50=9.44) and promoted Gα protein activation (pEC50=8.95).

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生物&药学活性

AM-8123 (AM8123) is a small-molecule agonist of Apelin receptor (APJ, APLNR), inhibits forskolin-stimulated cAMP production (pEC50=9.44) and promoted Gα protein activation (pEC50=8.95).

物理化学性质&存储条件

分子量	567.665
分子式	C27H33N7O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 1 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Pyrimidineethanesulfonamide, N-[4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl]-α,5-dimethyl-β-(1-methylethoxy)-, (αS,βS)-

参考文献

1. Brandon Ason, et al. JCI Insight. 2020 Apr 23;5(8):e132898.

AM-8123 (AM8123)

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物理化学性质&存储条件

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AM-8123 (AM8123)

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物理化学性质&存储条件

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