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首页-小分子抑制剂&激动剂-Others-Other Targets-AM-3607
AM-3607

Chemical Structure : AM-3607

CAS No.: 2098972-61-1

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AM-3607 (AM3607)

货号: PC-23983Not For Human Use, Lab Use Only.

AM-3607 is a potent, positive allosteric modulator of mammalian ionotropic glycine receptor (GlyR) subtypes with EC50 of 25 nM (hGlyRα3β), SPR Kd of 11 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AM-3607 is a potent, positive allosteric modulator of mammalian ionotropic glycine receptor (GlyR) subtypes with EC50 of 25 nM (hGlyRα3β), SPR Kd of 11 nM.

物理化学性质&存储条件

分子量 401.44
分子式 C19H19N3O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,3aS,9bS)-2-(Benzo[d][1,3]dioxol-5-ylsulfonyl)-3,5-dimethyl-3,3a,5,9b-tetrahydro-1H-pyrrolo[3,4-c][1,6]naphthyridin-4(2H)-one

参考文献

1. Bregman H, et al. J Med Chem. 2017 Feb 9;60(3):1105-1125.

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