ALX 5407 | GlyT1 inhibitor | Probechem Biochemicals

Chemical Structure : ALX5407

CAS No.: 571147-18-7

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ALX5407 ((+)-NFPS, ALX-5407)

货号: PC-61461Not For Human Use, Lab Use Only.

ALX 5407 ((+)-NFPS) is a potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS.

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5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3780	In stock
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100 mg		Get quote

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生物&药学活性

ALX 5407 ((+)-NFPS) is a is a potent, selective GlyT1 inhibitor that demonstrates >10-fold greater activity in in vitro functional glycine reuptake assay than racemic (±)-NFPS.
ALX 5407 ((+)-NFPS) is a induces a pattern of c-Fos immunoreactivity comparable with the atypical antipsychotic clozapine and enhanced prepulse inhibition of the acoustic startle response in mice.

物理化学性质&存储条件

分子量	393.45
分子式	C24H24FNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(3-([1,1'-biphenyl]-4-yloxy)-3-(4-fluorophenyl)propyl)-N-methylglycine

参考文献

1. Kinney GG, et al. J Neurosci. 2003 Aug 20;23(20):7586-91.

2. Huang B, et al. Cell Physiol Biochem. 2016;38(5):1952-62.

ALX5407 ((+)-NFPS, ALX-5407)

生物&药学活性

物理化学性质&存储条件

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ALX5407 ((+)-NFPS, ALX-5407)

生物&药学活性

物理化学性质&存储条件

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