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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glycine Transporter (GlyT)-ALX-1393
ALX-1393

Chemical Structure : ALX-1393

CAS No.: 949164-09-4

ALX-1393 (ALX 1393;ALX1393)

货号: PC-60446Not For Human Use, Lab Use Only.

ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM.

规格 价格 库存 数量
2 mg ¥2480 In stock
5 mg ¥3980 In stock
10 mg ¥5880 In stock
25 mg Get quote
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ALX-1393 (ALX 1393, ALX1393) is a potent, specific GlyT2 inhibitor with Ki of <1 uM.
ALX-1393 ameliorates dynamic and static mechanical allodynia in mice with herpetic or postherpetic pain, displays antinociceptive effects on in vivo.

物理化学性质&存储条件

分子量 395.43
分子式 C23H22FNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S)-2-amino-3-[(3-fluorophenyl)-(2-phenylmethoxyphenyl)methoxy]propanoic acid

参考文献

1. Morita K, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):633-45.

2. Nishikawa Y, et al. J Pharmacol Sci. 2010;112(3):352-60.

3. Jeong HJ, et al. Br J Pharmacol. 2010 Oct;161(4):925-35.

4. Eckle VS, et al. Neuroscience. 2013 Dec 3;253:165-71.

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