ALKBH5 inhibitor 20m

Chemical Structure : ALKBH5 inhibitor 20m

CAS No.: 126067-60-5

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货号: PC-38700Not For Human Use, Lab Use Only.

ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.

规格	价格	库存
5 mg	￥2980	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.
ALKBH5 inhibitor 20m exhibits high selectivity towards ALKBH5 versus FTO as well as other AlkB subfamily members (IC50>25 uM).
ALKBH5 inhibitor 20m could efficiently stabilize ALKBH5 and increase m6A level in intact cells.

物理化学性质&存储条件

分子量	270.211
分子式	C12H9F3N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-methyl-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid

参考文献

1. ZhenFang, et al. European Journal of Medicinal Chemistry, 11 May 2022, 114446.