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首页-小分子抑制剂&激动剂-Others-Other Targets-ALKBH5 inhibitor 20m
ALKBH5 inhibitor 20m

Chemical Structure : ALKBH5 inhibitor 20m

CAS No.: 1505579-77-0

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ALKBH5 inhibitor 20m (ALKBH5-IN-3)

货号: PC-38700Not For Human Use, Lab Use Only.

ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ALKBH5 inhibitor 20m is a potent, selective RNA m6A demethylase AlkB homolog 5 (ALKBH5) inhibitor with IC50 of 21 nM.
ALKBH5 inhibitor 20m exhibits high selectivity towards ALKBH5 versus FTO as well as other AlkB subfamily members (IC50>25 uM).
ALKBH5 inhibitor 20m could efficiently stabilize ALKBH5 and increase m6A level in intact cells.

物理化学性质&存储条件

分子量 272.18
分子式 C11H7F3N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid

参考文献

1. Fang Z, et al. Eur J Med Chem. 2022. PMID: 35597008

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