ALK5-IN-16i |CAS:864375-44-0 Probechem Biochemicals

Chemical Structure : ALK5-IN-16i

加入收藏

ALK5-IN-16i (ALK5 inhibitor 16i)

货号: PC-61453Not For Human Use, Lab Use Only.

ALK5-IN-16i is a potent and selective ALK5 inhibitor with IC50 of 5.5 nM, displays 300-fold selecitvity over ALK3.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

ALK5-IN-16i is a potent and selective ALK5 inhibitor with IC50 of 5.5 nM, displays 300-fold selecitvity over ALK3.
ALK5-IN-16i inhibits Smad2/3 phosphorylation in A549 cells (IC50=79 nM).
ALK5-IN-16i significantly decreases Smad2 phosphorylation in mouse skin after topical application.
ALK5-IN-16i may serves as a potential new therapy for AGA.

物理化学性质&存储条件

分子量	427.541
分子式	C20H21N5O2S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	isobutyl ((5-(benzo[d]thiazol-6-yl)-4-(4-methylthiazol-2-yl)-1H-imidazol-2-yl)methyl)carbamate

参考文献

1. Amada H, et al. Bioorg Med Chem. 2012 Dec 15;20(24):7128-38.

ALK5-IN-16i (ALK5 inhibitor 16i)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

ALK5-IN-16i (ALK5 inhibitor 16i)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.