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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldehyde Dehydrogenase (ALDH)-ALD1A3 inhibitor MF-7
ALD1A3 inhibitor MF-7

Chemical Structure : ALD1A3 inhibitor MF-7

CAS No.: 2582805-50-1

ALD1A3 inhibitor MF-7

货号: PC-20208Not For Human Use, Lab Use Only.

ALD1A3 inhibitor MF-7 is a specific ALD1A3 inhibitor with IC50 of 22.8 uM on recombinant human ALDH1A3.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    ALD1A3 inhibitor MF-7 is a specific ALD1A3 inhibitor with IC50 of 22.8 uM on recombinant human ALDH1A3.
    ALD1A3 inhibitor MF-7 exhibits anti-proliferative activity in the MDA-468 cell line.
    ALD1A3 inhibitor MF-7 reduces the levels of CD44 expression, prolongs survival and intercepts BM formation in mice.

    物理化学性质&存储条件

    分子量 288.33
    分子式 C19H13FN2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(4-fluorophenyl)-2-phenylimidazo[1,2-a]pyridine

    参考文献

    1. Yamashita D, et al. Mol Cancer Ther. 2020 May;19(5):1134-1147.

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