AKU-005 | Dual MAGL/FAAH inhibitor | Probechem Biochemicals

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Monoacylglycerol Lipase (MAGL)-AKU-005

Chemical Structure : AKU-005

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AKU-005 (AKU005)

货号: PC-20488Not For Human Use, Lab Use Only.

AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM.

规格	价格	库存	数量
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100 mg		Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AKU-005 is a potent, dual MAGL/FAAH inhibitor with IC50 of 589 and 309 pM for MAGL in rat and mouse brain membrane respectively, inhibits rat and human FAAH with IC50 of 63 and 389 nM.

物理化学性质&存储条件

分子量	347.42
分子式	C20H21N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4-benzhydrylpiperazin-1-yl)(1H-1,2,4-triazol-1-yl)methanone

参考文献

1. Niina Aaltonen, et al. Chem Biol. 2013 Mar 21;20(3):379-90.

2. Adriana Della Pietra, et al. J Headache Pain. 2023 Apr 11;24(1):38.

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AKU-005 (AKU005)

生物&药学活性

物理化学性质&存储条件

参考文献

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AKU-005 (AKU005)

生物&药学活性

物理化学性质&存储条件

参考文献

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