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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-AKR1C3 inhibitor 1
AKR1C3 inhibitor 1

Chemical Structure : AKR1C3 inhibitor 1

CAS No.: 3028287-26-2

AKR1C3 inhibitor 1

货号: PC-22254Not For Human Use, Lab Use Only.

AKR1C3 inhibitor 1 is a potent, selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with IC50 of 110 nM, 127-fold selective over AKR1C2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AKR1C3 inhibitor 1 is a potent, selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with IC50 of 43 nM, >2300-fold selective over AKR1C2.

物理化学性质&存储条件

分子量 371.44
分子式 C24H21NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(5-((4-methylbenzyl)carbamoyl)-[1,1'-biphenyl]-3-yl)acrylic acid

参考文献

1. Carmona AV, et al. Commun Chem. 2024 Apr 29;7(1):95.

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