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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-AKR1C3-IN-1
AKR1C3-IN-1

Chemical Structure : AKR1C3-IN-1

CAS No.: 327092-81-9

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AKR1C3-IN-1

货号: PC-28414Not For Human Use, Lab Use Only.

AKR1C3-IN-1 is a highly potent, selective inhibitor of AKR1C3 with IC50 of 13 nM.

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25 mg ￥580 In stock
50 mg ￥880 In stock
100 mg ￥1280 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AKR1C3-IN-1 is a highly potent, selective inhibitor of AKR1C3 with IC50 of 13 nM.
AKR1C3-IN-1 shows little to no activities against AKR1C1 (IC50=20.3 uM) and >30 μM against AKR1C2 and AKR1C4.
AKR1C3-IN-1 inhibits AKR1C3 activity (inhibiting PR-104H formation) with IC50 of 27 nM.

物理化学性质&存储条件

分子量 317.36
分子式 C16H15NO4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-((3,4-Dihydroisoquinolin-2(1H)-yl)sulfonyl)benzoic acid

参考文献

1. Jamieson SM, et al. J Med Chem. 2012 Sep 13;55(17):7746-58.

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