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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glycogen Synthase-AJS1669 sodium
AJS1669 sodium

Chemical Structure : AJS1669 sodium

CAS No.: N/A

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AJS1669 sodium (AJS-1669 sodium, AJS 1669 sodium)

货号: PC-60251Not For Human Use, Lab Use Only.

AJS1669 sodium is a potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AJS1669 sodium is a potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.
    AJS1669 shows no activity for GYS2.
    AJS1669 improves glucose metabolism and reduces body fat mass in mice.

    物理化学性质&存储条件

    分子量 535.494
    分子式 C26H20F2NNaO6S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate sodium salt

    参考文献

    1. Nakano K, et al. Int J Mol Med. 2017 Apr;39(4):841-850.

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