AJS1669 |CAS:1853130-05-8 Probechem Biochemicals

Chemical Structure : AJS1669

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AJS1669 (AJS-1669;AJS 1669)

货号: PC-60250Not For Human Use, Lab Use Only.

AJS1669 (AJS-1669) is a novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM.

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生物&药学活性

AJS1669 (AJS-1669) is a novel potent, allosteric, orally available muscle glycogen synthase 1 (GYS1) activator with EC50 of 5.2 uM; shows no activity for GYS2; improves glucose metabolism and reduces body fat mass in mice.

物理化学性质&存储条件

分子量	512.504
分子式	C26H20F2NO6S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-(((4',5'-difluoro-2'-(methylthio)-[1,1'-biphenyl]-4-yl)oxy)methyl)furan-2-carbonyl)-N-(furan-2-ylmethyl)glycinate

参考文献

1. Nakano K, et al. Int J Mol Med. 2017 Apr;39(4):841-850.

AJS1669 (AJS-1669;AJS 1669)

生物&药学活性

物理化学性质&存储条件

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AJS1669 (AJS-1669;AJS 1669)

生物&药学活性

物理化学性质&存储条件

参考文献

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