AH-23848 calcium salt | TP1/EP4 antagonist | Probechem Biochemicals

Chemical Structure : AH-23848 calcium salt

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AH-23848 calcium salt (AH23848, AH 23848)

货号: PC-70016Not For Human Use, Lab Use Only.

AH-23848 calcium salt is a dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM.

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100 mg		Get quote

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生物&药学活性

AH-23848 calcium salt is a dual antagonist of TP1 and EP4 receptors that inhibit TXA2-induced platelet aggregation with IC50 of 0.26 uM.
AH-23848 impairs PGE2-mediated relaxation of piglet saphenous vein by antagonizing the PGE2 receptor EP4.

物理化学性质&存储条件

分子量	496.6
分子式	C29H34NO5 • 1/2Ca
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-7-((1S,2S,5R)-5-([1,1'-biphenyl]-4-ylmethoxy)-3-oxo-2-(tetrahydro-2H-pyran-4-yl)cyclopentyl)hept-4-enoic acid

参考文献

1. Brittain RT, et al. Circulation. 1985 Dec;72(6):1208-18.

2. Coker SJ, et al. Br J Pharmacol. 1985 Sep;86(1):259-64.

3. Qian X, et al. J Biol Chem. 2011 Jan 21;286(3):2111-20.

AH-23848 calcium salt (AH23848, AH 23848)

生物&药学活性

物理化学性质&存储条件

参考文献

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AH-23848 calcium salt (AH23848, AH 23848)

生物&药学活性

物理化学性质&存储条件

参考文献

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