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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-RAR/RXR-AGN196996
AGN196996

Chemical Structure : AGN196996

CAS No.: 958295-17-5

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AGN196996 (AGN 196996, IRX-6696, IRX6696)

货号: PC-21162Not For Human Use, Lab Use Only.

AGN 196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.

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5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AGN196996 (IRX6696) is a potent selective RARα antagonist with Ki of 2 nM, shows little to no activity against RARβ and RARγ.
AGN196996 (IRX6696) blocks the gene transcriptional activity induced by ATRA and other RAR agonists.

物理化学性质&存储条件

分子量 482.33
分子式 C24H20BrNO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-[[3-Bromo-4-ethoxy-5-(4-methylbenzoyl)benzoyl]amino]benzoic acid

参考文献

1. Hammond LA, et al. Br J Cancer. 2001 Aug 3;85(3):453-62.

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