AGI-41998 | MAT2A inhibitor | Probechem Biochemicals

Chemical Structure : AGI-41998

CAS No.: 2377492-26-5

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货号: PC-21474Not For Human Use, Lab Use Only.

AGI-41998 is a potent selective and brain-penetrant methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 22 nM.

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AGI-41998 is a potent selective and brain-penetrant methionine adenosyltransferase 2A (MAT2A) inhibitor with IC50 of 22 nM.

分子量	505.30
分子式	C22H16BrF3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrido[4,3-d]pyrimidin-7(6H)-one, 8-(4-bromophenyl)-6-(4-methoxyphenyl)-2-[(2,2,2-trifluoroethyl)amino]-

1. Mingzong Li, et al. J Med Chem. 2022 Mar 24;65(6):4600-4615.