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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-AG-0029
AG-0029

Chemical Structure : AG-0029

CAS No.: 1715916-58-7

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AG-0029 (AG0029)

货号: PC-20169Not For Human Use, Lab Use Only.

AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    AG-0029 is a highly potent agonist of dopamine D2/D3 receptor (EC50=0.08 nM) and a moderate affinity antagonis of H3 receptor (IC50=111 nM).
    AG-0029 could meliorate both the motor and cognitive symptoms of parkinson's disease (PD).

    物理化学性质&存储条件

    分子量 452.56
    分子式 C25H32N4O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    7-(4-(3-(4-(morpholinomethyl) phenoxy)propyl)piperazin-1-yl) benzo[d]oxazol-2(3H)-one

    参考文献

    1. Ghazanfari N, et al. Mol Pharm. 2022 Jul 4;19(7):2287-2298.

    2. Patent WO2015069110.

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