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首页-小分子抑制剂&激动剂-Others-Other Targets-AF40431
AF40431

Chemical Structure : AF40431

CAS No.: 181125-92-8

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AF40431 (AF 40431;AF 40431)

货号: PC-35821Not For Human Use, Lab Use Only.

AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

AF40431 (AF-40431) is the first reported small-molecule ligand of the VPS10P family sorting receptor Sortilin with IC50 of 4.4 uM, binds in the neurotensin-binding site of sortilin.

物理化学性质&存储条件

分子量 319.357
分子式 C17H21NO5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

((7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl)-L-leucine

参考文献

1. Andersen JL, et al. Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):451-60.

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