AF-353 | P2X3 antagonist | Probechem Biochemicals

Chemical Structure : AF-353

CAS No.: 865305-30-2

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货号: PC-62754Not For Human Use, Lab Use Only.

AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively.

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AF-353 (RO-4) is a potent, selective and drug-like dual P2X3 and P2X2/3 antagonist with pIC50 of 8.0 and 7.1, respectively.

分子量	400.22
分子式	C14H17IN4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(5-iodo-2-isopropyl-4-methoxyphenoxy)pyrimidine-2,4-diamine

1. Jung YH, et al. ACS Chem Neurosci. 2017 Jul 19;8(7):1465-1478.