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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-YAP-TEAD-AF-2112
AF-2112

Chemical Structure : AF-2112

CAS No.:

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AF-2112 (AF2112)

货号: PC-21253Not For Human Use, Lab Use Only.

AF-2112 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

AF-2112 is a small molecule inhibitor of TEAD, reduces the expression of CTGF, Cyr61, Axl and NF2, inhibits migration of human MDA-MB-231 breast cancer cells.

物理化学性质&存储条件

分子量 351.38
分子式 C21H18FNO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-fluoro-2-((3-phenethoxyphenyl)amino)benzoic acid

参考文献

1. Ahmed Fnaiche, et al. Bioorg Med Chem Lett. 2023 Oct 15:95:129488.

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